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Phospholipase D3 degrades mitochondrial DNA to regulate nucleotide signaling...

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New frontiers in quality control: the case of GPI-anchored proteins

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Studying lysosomal function and dysfunction using LysoIP

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Multi-omic approach characterises the neuroprotective role of retromer in...

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Apicobasal RNA asymmetries regulate cell fate in the early mouse embryo

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Loss of the batten disease protein CLN3 leads to mis-trafficking of M6PR and...

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SCP2 mediates the transport of lipid hydroperoxides to mitochondria in...

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Hypoxia-reprogramed megamitochondrion contacts and engulfs lysosome to...

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Lysosomal cystine export regulates mTORC1 signaling to guide kidney...

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Inhibition of CysLTR1 reduces the levels of aggregated proteins in retinal...

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Balancing lysosome abundance in health and disease

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Tubular lysosome induction couples animal starvation to healthy aging

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Cell cycle-linked vacuolar pH dynamics regulate amino acid homeostasis and...

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A yeast vacuolar pH ‘heartbeat’ coordinates amino acid metabolism and the...

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Lysosomes mediate the mitochondrial UPR via mTORC1-dependent ATF4...

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Disease pathology signatures in a mouse model of Mucopolysaccharidosis type IIIB

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Sec22b regulates phagosome maturation by promoting ORP8-mediated lipid...

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Surviving salt stress

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Sulforaphane decreases serum selenoprotein P levels through enhancement of...

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The transcription factor Zeb1 controls homeostasis and function of type 1...

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